A comparative study on erlotinib & gefitinib therapy in non-small cell lung carcinoma patients

P Thomas, B Vincent, C George… - Indian Journal of …, 2019 - journals.lww.com
study showed that erlotinib and gefitinib had similar effectiveness but gefitinib had a better
safety profile compared to erlotinib… for NSCLC patients compared to erlotinib. However, further …

Comparison of gefitinib, erlotinib and afatinib in non‐small cell lung cancer: a meta‐analysis

Z Yang, A Hackshaw, Q Feng, X Fu… - … journal of cancer, 2017 - Wiley Online Library
… if the comparative effects of gefitinib versus erlotinib would vary with these important clinical
factors and to explore the source of substantial heterogeneity, if present. Sensitivity analyses …

Comparative study of radiotherapy plus erlotinib versus chemoradiotherapy for elderly patients with esophageal cancer: a propensity score-matched analysis.

T Song, D Du, X Zhang, M Fang… - Diseases of the …, 2017 - search.ebscohost.com
… In conclusion, the present study suggested radiotherapy plus erlotinib should be a
preferable modality compared with CCRT, with similar survival outcomes but better treatment …

[HTML][HTML] A retrospective comparison of the clinical efficacy of gefitinib, erlotinib, and afatinib in Japanese patients with non-small cell lung cancer

A Fujiwara, M Yoshida, H Fujimoto, H Nakahara… - Oncology …, 2018 - ncbi.nlm.nih.gov
… (gefitinib, erlotinib, … , erlotinib, or afatinib is most appropriate as a first-line therapy is still a
controversial issue. The aim of this study was to compare the effectiveness of gefitinib, erlotinib, …

Comparative studies on the human serum albumin binding of the clinically approved EGFR inhibitors gefitinib, erlotinib, afatinib, osimertinib and the investigational …

O Dömötör, K Pelivan, A Borics, BK Keppler… - … of Pharmaceutical and …, 2018 - Elsevier
… Therefore, we aimed to study the interaction of OSI and the experimental drug KP2187 from
… Herein we report on an extensive comparative study of the EGFR inhibitors regarding their …

[HTML][HTML] Tyrosine kinase inhibitors show different anti-brain metastases efficacy in NSCLC: a direct comparative analysis of icotinib, gefitinib, and erlotinib in a nude …

J Tan, M Li, W Zhong, C Hu, Q Gu, Y Xie - Oncotarget, 2017 - ncbi.nlm.nih.gov
erlotinib, and icotinib, are reported to be effective in patients with brain metastases. However,
direct comparative studies … to brain metastases more effectively than erlotinib or icotinib in a …

Comparison of effectiveness and adverse effects of gefitinib, erlotinib and icotinib among patients with non‑small cell lung cancer: A network meta‑analysis

Y Liu, Y Zhang, G Feng, Q Niu… - Experimental and …, 2017 - spandidos-publications.com
… rates compared with erlotinib (P<0.05). Erlotinib resulted in a significantly longer MST
compared with gefitinib and icotinib (P<0.05). In conclusion, gefitinib, erlotinib and icotinib had …

… advanced non–small cell lung cancer patients with EGFR mutations in response to first-line treatment with two EGFR-TKIs, gefitinib and erlotinib: a comparative study

MX Li, H He, ZH Ruan, YX Zhu, RQ Li, X He, BH Lan… - BMC cancer, 2017 - Springer
… with erlotinib compared with gefitinib. If confirmed, our results indicate that erlotinib may
play an important role in controlling CNS progression from EGFR mutation-positive NSCLC. …

Gefitinib provides similar effectiveness and improved safety than erlotinib for east Asian populations with advanced non–small cell lung cancer: a meta-analysis

W Zhang, Y Wei, D Yu, J Xu, J Peng - BMC cancer, 2018 - Springer
… Almost all of the included studies did not show any differences in all anti-… study reported an
unfavorable result for erlotinib, with both lower PFS and OS, which might relate to the erlotinib

Gefitinib provides similar effectiveness and improved safety than erlotinib for advanced non-small cell lung cancer: A meta-analysis

W Zhang, Y Wei, D Yu, J Xu, J Peng - Medicine, 2018 - journals.lww.com
studies showed no differences in all indices of antitumor effectiveness, which was the basis
of our results. Only one study reported an unfavorable result against erlotinib, … in the erlotinib